Could you please post Development help in the Development forum.
As for the problem, you need msvcr100.dll in the same folder as the powder toy executable, You can find it on your own computer by doing a search, or use the one provided in powder toy download in this website.
Easy fix :p if a program complains a dll is missing... put the dll in the folder lol.
download it (if you don't already have it), extract the dll to the folder (or in singularities case, add it to your zip already) and it runs fine (tested it myself)